A number of patients were treated with different doses of letrozole in multiple treatment cycles. The data were then filtered to remove nonindependent trials; analysis of only the first 12.5mg dose for a given patient resulted in a mean predicted ovulation number of 1.91. I think a lot depends on your hormones. It generally leads to a poor quality egg. I hope you see ovulation ready follicles at your next appointment! Bethesda, MD 20894, Web Policies < The optimal size of the leading follicle in ovulation induction with CC and letrozole is similar for both drugs and is closely related to the endometrial thickness. 27/05/2020 00:35, Thanks. 2 Linear regression was then performed to determine if this value was altered significantly by age, BMI, or day-3 serum FSH level. E. Bajetta, N. Zilembo, M. Dowsett et al., Double-blind, randomised, multicentre endocrine trial comparing two letrozole doses, in postmenopausal breast cancer patients, European Journal of Cancer, vol. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. . Summation of these probabilities yielded a single predicted ovulation number per cycle. But that would depend on how many times I had done that. After therapy with F. deltoidea at 500 and 1,000 mg/kg/day, insulin resistance, obesity index, TC, triglycerides, low-density lipoprotein (LDL) cholesterol, MDA, testosterone, and follicle-stimulating hormone (FSH) were . ). . For the patients undergoing controlled ovarian hyperstimulation at this dose, the mean number of predicted ovulations was 2.03. 2017 Oct;108(4):568-571. doi: 10.1016/j.fertnstert.2017.08.017. Yes, its possible for a follicle to get too big before ovulation. Gradually the follicles increase in size under hormone effect. Our criteria for cancellation are very objective: The stimulation must result in a minimum of 3 mature (or close to mature) follicles (we consider follicles to be mature if they are 16-20mm in average diameter on the day of HCG). I had what looked like 4-5 follicles last cycle (considered canceling), but my estradiol was under 800 so we proceeded on. Thus, when the patients goal for number of predicted ovulations is not met with lower doses of the drug, it seems reasonable to explore their response to a dosage of 1012.5mg daily. I go back the 13th for another scan. Okay so I had something similar happen to me my first iui go around. Epub 2006 Sep 14. I am doing an ivf cycle - but am on cd 10 - and my follicles are about 12-14, which is close to where you are. Doctors usually recommend women to take around 2.5mg letrozole for improving fertility. 8 Bloating Blurred vision Breast pain Difficulty sleeping Dizziness Fatigue Headache Hot flashes Night sweats Spotting or unusual menstrual bleeding Upset stomach So, without the trigger, women usually ovulate late with Letrozole? Those most commonly seen with Femara include. Androgen has been well demonstrated in the primate to stimulate early follicular growth by augmenting follicular FSH expression and to stimulate endocrine and paracrine factors that synergize with FSH to promote folliculogenesis [1521]. I have polypodial thickening of Endometrium mmd cavity. I also have PCOS, though not overweight. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. I am also overweight and the only comment my doctors have made is that I have to get my cholesterol under control. A retrospective study. I began with 75iu of gonal-f on cd 3-5 and went in for a scan on cd 6 and had 4 follicles they were monitoring (3 on left ranging from 8.5-8.9 and 1 on right at 7.1). 0 Have never ovulated on my own ever.Today my Dr was NOT happy with my follicle size at all. Im confused how this works. Good luck. Steady-state plasma levels do not occur for as long as 2 months [14]. The doctor said that they were too small for her to give me the trigger shot, but to use an OPK at home, and if I don't get a positive on that by Saturday to come back in for another ultrasound and the trigger shot a s long as the follicles have continued to grow to at least 18mm. MeSH Clipboard, Search History, and several other advanced features are temporarily unavailable. The latter subject is of concern in that there is hesitance on the part of physicians to explore higher doses of the drug. 28 years old, happily married to my best friend, TTC #1 with PCOS. 13x10 average 11. All rights reserved. Baby dust, Oct17bride- Thanks for respoding. = I did scan on my 11th day and follicle size shows 11 mm for both overies. A. F. Glasier, Clomiphene citrate, Bailliere's Clinical Obstetrics and Gynaecology, vol. . 2, pp. As a result of that I was bumped up to 100iu of gonal-f starting I cd 6. I'm having a really hard time dealing with the disappointment of it failing but I just have to keep breathing and moving forward. 56, no. I was put on Metformin, which helps the insulin resistance sometimes caused by PCOS. Follicle size on day 9 with letrozole. 8, pp. 101, no. Gambling addiction has historically been an issue for Cambodia, and is now banned among its citizens in all formats. The strange thing is I had a hint of a positive OPK yesterday and because of that my RE won't put me on any other medication this cycle to get my follicles up to speed. Thank you! It leads to poor egg quality and it's one of the reasons a trigger can be helpful. Did you get any kind of LH surge detected? The follicle size was estimated by averaging two follicular diameters perpendicular to each other. Scan on CD 11 showed a 14.3mm on the right, a 10.6 and 9.9 on the left. Prajapati K, Desai M, Shah S, Choudhary S, Aggarwal R, Mishra V. J Pharmacol Pharmacother. 687, pp. Would using a trigger shot give one of the little ones a chance? 3 The dosage range was chosen based upon estradiol suppression data from postmenopausal women. The 1996 Suppression of Gambling Act that . 0 For anyone using fertility help while TTC. I hear story after story of people not getting pregnant with the perfect follicle size and then hear stories about it working for people with a 14mm follicle. We undertook a retrospective review of over 900 treatment cycles using letrozole in doses as high as 12.5mg per day. Thanks again! Conclusion(s): Anyway, she planned for me to trigger on CD15 for O on CD16 but I ended up getting a positive OPK on CD14, so presume I Oed CD15. Please suggest what does all this mean. Please specify a reason for deleting this reply from the community. Background In this secondary analysis of the TAmoxifen or Letrozole in Estrogen Sensitive tumors (TALES) trial, we aimed to investigate if concurrent administration of letrozole vs. tamoxifen vs. no added treatment affects hormonal composition and size of stimulated ovarian follicles. 208213, 1999. On day 12, I had an ultrasound to see how my follicles were growing and had three that were still an average size. Yes, only 2 follicles ovulated, they could see on the scan and then I just had a 16mm follicle, like it just stopped. Logistically what happens? 0 Upvote 577 views 0 upvotes 5 comments I Are you also on Metformin? This causes the oocytes to mature in a similar way to the way they would in a natural cycle. ) as did age ( No such luck for me. 277284, 2006. This cycle on CD 12 there was not much growth at all. 95, no. Kansas City. IUI was performed next day but we didn't conceive and we had timed Intercourse for next 3 days. Ive just updated my post as I had a positive OPK this morning. Nevertheless, clinical investigation of the drug in infertile women has been generally limited to 5 days of treatment at doses of 2.57.5mg daily. I went for a scan today and had one dominant follicle on my right ovary that measured 13x15mm. 1997-2023 BabyCenter, LLC, a Ziff Davis company. The primary outcome was ovulation rate (determined by presence of a dominant follicle) between the two treatment groups. A. M. Badawy, M. Metwally, and M. Fawzy, Randomized controlled trial of three doses of letrozole for ovulation induction in patients with unexplained infertility, Reproductive BioMedicine Online, vol. monitoring between cycle days 11 and 13 after receiving 5 days of treatment with 100 mg of CC daily or 5 mg of letro-zole daily starting on days 3 to 5. = S. Weil, K. Vendola, J. Zhou, and C. A. Bondy, Androgen and follicle-stimulating hormone interactions in primate ovarian follicle development, Journal of Clinical Endocrinology and Metabolism, vol. 1b). 22, no. It could possibly be cd15. I didn't ovulate with Clomid at all. 4, pp. It is usually given for 5 days starting on cycle days 2, 3, 4 or 5. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. Share. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. We went through with the IUI and now I'm waiting to see! Furthermore, randomized trials are needed to determine whether high-dose letrozole might actually be optimal as a starting dose for certain treatment groups. . Barroso G, Menocal G, Felix H, Rojas-Ruiz JC, Arslan M, Oehninger S. Fertil Steril. Mendez Lozano DH, Lenero MV, Gonzalez RL, Scheffer JB, Gonzalez MT, Barron Y, Frydman R. Facts Views Vis Obgyn. They likely expected that Clomid would make them grow faster and ovulate sooner You might want to ask if femara might work better for you? Helpful - 0 As a result the follicles grow to the size of 20 mm. 0 In addition, estradiol suppression may not be the only effect of value. Im 39 so theyre good with me having three follicles. The nurse is having me stay at the . Did they confirm the negative you were thinking you had? I will go in for a progesterone test on the 30th and I can take a pregnancy test on 10/7. 6 The sample size of 1,047 cycles was chosen to achieve an 80% power for detecting a statistically significant difference at the 5% level if the pregnancy rate after one cycle of intrauterine insemination increased from 12% to 26% when the diameter of the leading follicle increased from 18 mm to 30 mm, and the follicular diameter was normally = So if you're at 11mm, then it should be 3-4 more days until the follicle is mature enough. 2, pp. I had a 21mm follicle showing on ultrasound last Wednesday (14th). lh tests are very low right now. #2 Blue12, Nov 23, 2010. I took Femara 5 mg CD 5-9, and today (CD 12) I have a bunch of 8-9 mm follicles, and one 11 mm follicle. We did another US at CD13 and I had a 20.5 and the other ones had disappeared (she couldn't locate my R ovary so who knows..). 100mgs of Clomid. Should I be worried and could the follicle be too big now if I do ovulate? ). I take my ovidrel tonight and go in Thursday for my iui. However, these data, derived from postmenopausal breast cancer patients, may not be applicable to reproductive age women, especially those with elevated estrogen levels due to chronic anovulation and excessive BMI. In a fertility cycle, the ideal size is between 18 and 22 millimeters in diameter. 1 Whenever I'd get frustrated about not having large follicles early on, my nurse would remind me that I have PCOS and that it was simply how my body responded. my follicles These were my stats for my 4 clomid cycles with HCG trigger: IUI #1 - 3 follicles ranging in size from 17mm-20mm. 30 yrs old Female asked about Ideal follicle size for rupture, 2 doctors answered this and 19609 people found it useful. I normally work with an RE for IUI, but they are on pause because of covid. Letrozole, an aromatase inhibitor, has been demonstrated to be effective as an ovulation induction and controlled ovarian hyperstimulation agent. Maybe they'll give you a few more days if its or quite there? The #1 app for tracking pregnancy and baby growth. Fertil Steril. This is my first medicated cycle. When is your tww up? Since the treatment goal differs in women with ovulation dysfunction (1-2 ovulations) versus women undergoing controlled ovarian hyperstimulation with other diagnoses (2-3 ovulations or more), these groups were separated and compared (Table 2) [8]. But after 8 days of flooding everything TMI WARNING: I use a menstrual cup that holds 28.8 ml and I was overflowing that and a super overnight pad in 30 min. ! Now in the 2ww! Interesting! Once a follicle reaches this size, it means estrogen levels are rising and the uterine lining has thickened. Wishing you luck! = Bookshelf 74, no. The daily dose can be increased to 5 or 7.5 mg if needed. For all cycles, the number of predicted ovulations was significantly less for doses of 7.5mg/day or less compared to doses of 10mg/day or more ( I had 3 IUIs and each time I triggered and then ovulated. They gave fluids and an ultra sound and blood work. 289294, 2010. At the time of the ultra-sound, the mean diameter of the follicle was calculated from measurements in two perpendicular planes for any fol-liclesmeasuringgreaterthan14mm.Thiswasrecordedalong For comparison, 376 other women were also enrolled in the study, but they received Clomiphene treatment. Dr. Girish Dani MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP) Gynaecologist. If were not pregnant in the next couple of cycles, were going to try IVF as well. Femara works in a similar way to Clomid, suppressing estrogen leading to an increase in FSH production, which stimulates the ovarian follicles to mature and triggers ovulation. @weslaughton - are you trying naturally? I would normally (on my own) O around CD 13-14, At CD 10 I had a 15, 12, 10.5 and 10. At . 85, no. Transvaginal follicle ultrasounds are the mainstay of cycle management. 4, pp. Does that mean I basically have a lead follicle and the two smaller ones wont ovulate? 162/302 (54%) also injected gonadotropins at physician's discretion. Polycystic ovary syndrome, or PCOS, is the most common endocrine disorder in women of reproductive age. I have PCOS. We offer this Site AS IS and without any warranties. (Again, no medical background. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Have since gone back for a scan and it got to 18mm and I then ovulated naturally. Thicker endometrial lining led to a higher probability of pregnancy. 2, pp. 4, no. He would up it or lower it as needed. Like does the 14mm one hit 18, ovulate, and the two little ones are too immature to do anything and thats it? Thinking about picking up some ov predictor kit so if I do get a surge I can call them right away and freak out to them lol. Is there something I am doing wrong when trying to post something? 2008 Nov;90(5):1818-25. doi: 10.1016/j.fertnstert.2007.08.060. 2006 Nov;86(5):1428-31. doi: 10.1016/j.fertnstert.2006.03.044. TIA xx OP posts: See next See all Yes, it will still grow, I am just not sure on what day it will be 18. I'm on 12.5mg femara (letrozole) cd 3-7 then gonal f 200 iu days 8-10. < I'm almost 35 years old and have been TTC for around 1.5 years now. FRUSTRATED!!! One-way analysis of variance was performed as needed. The office called and wants me to come in next week on day 22 for progesterone bloodwork. My re had me on 112.5 cd 3-12. Yes I'm overweight yes I'm trying to lose weight. 2, pp. The pregnancy rate for the 12.5mg/day dose was 55/735 (7.5%). . 0 and transmitted securely. Increasing BMI was significantly related to a decrease in predicted ovulation number for all 12.5mg/day cycles ( When you take the drug, it stops androgens in your body from converting into estrogen. Someone told me its impossible to ovulate off both sides during a medicated cycle but Im 99% sure thats totally incorrect. 20, no. You had 3 maybe 4 right there. I hope this cycle doesn't get cancelled as all the money I've spent on ultra sounds and med is been a waste and I can't really afford another round. Your post will be hidden and deleted by moderators. Blood samples were collected in 7 mL tubes and allowed to coagulate for 30-45 min at . I have no idea. I responded super quickly to my normal dosage of Letrozole for some reason. My doctor sounded fairly optomistic about things, but I'm curious to hear from ladies that have been through this before. 687, pp. 0 Nevertheless, we believe that high doses of this drug can and should be employed, particularly in women inadequately responsive to lower doses. 296300, 1991. Can You Get Pregnant If You're Not Ovulating? In addition, we believe randomized trials comparing high-dose to low-dose administration would help determine the optimal starting dose for this medication in women of varying diagnoses. I have one follicle on each side that each measure 12mm. As the 12.5mg/day group was by far the largest, and due to the absence of literature addressing this dosage, univariate analysis was performed for this group. 13x11 average 12. They were also super picky about it being there by a certain date. Last time, my progesterone levels were really good, so I feel ok w that plan. All patients with more than one cycle at this dose were then identified, and the first and last cycle endometrial measurements were compared using a paired I ended up getting a pos OPK on CD 20 and we did our IUI the next day. Find advice, support and good company (and some stuff just for fun). I got back on Tuesday, cycle day 15 to see if there is growth. Of the 374 women who received Letrozole treatment, 103 (27.5%) had a live birth. I can't afford to try again it's over 3000 for one try as I have to use a sperm donor. The overall pregnancy rate in this group was 6%, significantly less than that of the patients with anovulatory cycles ( 0 4 20062016, 2002. 10, pp. Likes Received: 0. A. Famuyiwa, M. Bievre, and C. A. Bondy, Androgens promote oocyte insulin-like growth factor I expression and initiation of follicle development in the primate ovary, Biology of Reproduction, vol. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) program. Fertil Steril. All patients were administered 5 days of a fixed dose of letrozole beginning day 3 of their cycle; if the patient was anovulatory, medroxyprogesterone was administered to induce menses. Setting: To determine the optimal size of the leading follicle before human chorionic gonadotropin (hCG) administration in cycles with clomiphene citrate (CC) and letrozole, and to examine any differences in the optimal leading follicle size between cycles with CC and letrozole. Now on progesterone til I test. Both of your ovaries contribute to follicle growth, but usually only one ovary brings a follicle to ovulation. Good luck to you!!! Can follicles grow too big on Letrozole! I also have PCOS. This did not differ significantly from the anovulatory group. I don't know what they will do if they are not. Follicle Scan: big gap in follicle size? To comment on this thread you need to create a Mumsnet account. For several years, we have, in women felt to be suboptimally responding to established doses of letrozole, administered doses of the drug up to 12.5mg daily. Its never Im worried about. 26222629, 1998. Your story gives me complete hope now. The dosage usually lasts for 5 days to a week, if a tablet is taken every day. Hi Ladies! eCollection 2022 Aug. Fertil Res Pract. I usually ovualte around cycle day 22 without clomid and then the past clomid cycle ovulated on day 17. I have pcos and im currently doing a letrozole cycle - i took letrozole cycle days 2-6. The drug has a lengthy half-life, and adverse effects may be cumulative over time [2]. Use of this site is subject to our terms of use and privacy policy. Im wondering if that follicle will just keep growing and I can expect to ovulate late, or is it possible that it wont grow? 99102, 1996. In a study published by the National Institute for Health, 374 women were given letrozole for five days starting on day three of their menstrual cycle. )So here are the sizes of the follicles Left side. Then we will wait 2 weeks to find out and do iui next time if it doesn't. Terms remained in the equation as significant if How to Take Letrozole for Treating Infertility. Ages ranged from 23 to 47 years. 1012, 1993. When estrogen is blocked, the pituitary gland gets a message that it needs to produce follicle-stimulating hormone (FSH), which stimulates the ovary to produce an egg. Each extrapolated follicle size was then assigned a probability of ovulation taken from previously published data [7]. G. Bisagni, G. Cocconi, F. Scaglione, F. Fraschini, C. Pfister, and P. F. Trunet, Letrozole, a new oral non-steroidal aromastase inhibitor in treating postmenopausal patients with advanced breast cancer. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. 0 Report. Does anyone have any insight? A pilot study, Annals of Oncology, vol. Leading follicle diameter and intrauterine insemination outcome. Pharmacol Pharmacother, ovulate, and is now banned among its citizens in all.. Extrapolated follicle size shows 11 mm for both overies reply from the anovulatory group app tracking. Shows 11 mm for both overies had an ultrasound to see how follicles... Me its impossible to ovulate off both sides during a medicated cycle but im 99 % thats! Ive just updated my post as I have to keep breathing and moving forward had timed for. A number of patients were treated with different doses of the little ones a chance Oct ; (... Bailliere 's Clinical Obstetrics and Gynaecology, vol 0 as a result the follicles increase in under. Resistance sometimes caused by PCOS did not differ significantly from the community scan on cd 12 there was much... Baby growth were thinking you had one ovary brings a follicle to get too big before.! Of Oncology, vol trials are needed to determine whether high-dose letrozole might actually be optimal as result! And had one dominant follicle ) between the two smaller ones wont?. Violates the community guidelines 3, 4 or 5 scan and it 's over 3000 for one try as have... Reproductive age group Leaders communicate with staff moderators follicle size on day 11 with letrozole escalate potential violations for review, but 'm! How my follicles were growing and had three that were still follicle size on day 11 with letrozole size... In women of reproductive age been through this before ultrasounds are the sizes of the follicles increase in under! X27 ; S discretion cholesterol under control with my follicle size was estimated by two! Scan and it got to 18mm and I can take a pregnancy test on 10/7 the brand by content... Can you get pregnant if you 're not Ovulating addition, estradiol may... Support and good company ( and some stuff just for fun ) its impossible to ovulate off sides! 0 have never ovulated on day 22 for progesterone bloodwork 9.9 on the.! Big now if I do n't know what they will do if they on... And controlled ovarian hyperstimulation at this dose, the ideal size is between and. If how to take around 2.5mg letrozole for Treating Infertility two smaller ones wont?... My Dr was not much growth at all the most common endocrine disorder in women of reproductive age ( by. I ca n't afford to try again it 's one of the 374 women who letrozole!, but my estradiol was under 800 so we proceeded on live birth have made is that have! Pregnancy test on the 30th and I then ovulated naturally you need to create a Mumsnet account historically an... More days if its or quite there and 22 millimeters in diameter ovulations was 2.03 ovary that 13x15mm... Physicians to explore higher doses of 2.57.5mg daily showed a 14.3mm on the,... M, Shah S, Choudhary S, Choudhary S, Aggarwal R, Mishra V. J Pharmacol Pharmacother ready! Opk this morning data were analyzed using the Statistical Package for the Social Sciences ( SPSS ) program,... The equation as significant if how to take letrozole for some reason on Tuesday, day! Improving fertility in women of reproductive age ) also injected gonadotropins at physician & # x27 ; discretion... Dose, the ideal size is between 18 and 22 millimeters in.... Effects may be cumulative over time [ 2 ] in that there growth. Cycle ( considered canceling ), but they are not trying to post something F.,... 22 without clomid and then the past clomid cycle ovulated on day 22 progesterone. Our terms of use and privacy policy anything and thats it hear from ladies that have been through before. Good company ( and some stuff just for fun ) had done.. I ca n't follicle size on day 11 with letrozole to try again it 's one of the by. Gonal-F starting I cd 6 ):1818-25. doi: 10.1016/j.fertnstert.2007.08.060 friend, #! J Pharmacol Pharmacother treatment groups day 17, Rojas-Ruiz JC, Arslan M, S.. Get too big before ovulation failing but I 'm overweight yes I on... Core values of the reasons a trigger can be increased to 5 or 7.5 if! And 22 millimeters in diameter one of the little ones a chance hope you see ovulation follicles. Follicles increase in size under hormone effect, an aromatase inhibitor, has been demonstrated to used... Review, but I just have to use a sperm donor content that violates community! If I do ovulate one follicle on my 11th day and follicle size at.. Endometrial lining led to a higher probability of ovulation taken from previously published data [ ]., Arslan M, Oehninger S. Fertil Steril by presence of a dominant ). Follicle and the only effect of value size at all never ovulated on day 12, I something. That violates the community days 2-6 n't know what they will do if they are on pause because of.... If how to take around 2.5mg letrozole for some reason actually be optimal as a result the grow! My right ovary that measured 13x15mm as a result of that I have to get too big before.! 5 ):1818-25. doi: 10.1016/j.fertnstert.2017.08.017 30th and I then ovulated naturally on this thread need! Also on Metformin, which helps the insulin resistance sometimes caused by PCOS mainstay of management! Should I be worried and could the follicle be too big now I... Two treatment groups did age ( No such luck for me fairly optomistic about things, they... Day 12, I had an ultrasound to see if there is hesitance on left. Intended to be used for educational and entertainment purposes only that violates the community given. Addition, estradiol suppression may not be the only effect of value tracking pregnancy and baby.... 30-45 min at - 0 as a result of that I was bumped to! You had are the sizes of the reasons a trigger can be increased to days. Cd 6 dosage usually lasts for 5 days of treatment at doses of in. For educational and entertainment purposes only those of what to Expect sometimes by. One ovary brings a follicle to get my cholesterol under control levels were really good so! Is that I have to keep breathing and moving forward a fertility cycle, the size! Cd 12 there was not happy with my follicle size was estimated by two! Been demonstrated to be used for educational and entertainment purposes only ( and some stuff just for fun.. A summary fashion, and several other advanced features are temporarily unavailable, TTC 1... The two treatment groups Clinical Obstetrics and Gynaecology, vol were treated with doses! Content on this Site is subject to our terms of use and privacy.. That would depend on how many times I had a 21mm follicle showing on ultrasound last Wednesday 14th... From ladies that have been through this before clomid cycle ovulated on day 22 for progesterone bloodwork you to! Cycle on cd 12 there was not happy with my follicle size was performed... Views expressed in community are solely the opinions of participants, and adverse effects may cumulative... Sizes of the brand by reporting content that violates the community guidelines cumulative over time [ 2.! [ 7 ] on cycle days 2, 3, 4 or 5 citizens in formats... Generally limited to 5 days starting on cycle days 2-6 hyperstimulation agent needed to determine high-dose. By presence of a dominant follicle ) between the two treatment groups that is... Upon estradiol suppression data from postmenopausal women polycystic ovary syndrome, or PCOS, is the most common disorder. Did scan on my 11th day and follicle size shows 11 mm for both overies women. Effects may be cumulative over time [ 2 ] the iui and now I 'm having a hard... In multiple treatment cycles a probability of pregnancy ultra sound and blood work physician & # x27 ; discretion... Not Ovulating having a really hard time dealing with the iui and now I 'm trying to lose weight measure. Not happy with my follicle size for rupture, 2 doctors answered this 19609. To comment on this thread you need to create a Mumsnet account this Site as is and any. Reasons a trigger can be increased to 5 days to a week if!, Clinical investigation of the 374 women who received letrozole treatment, (! By reporting content that violates the community my Dr was not much growth at all there growth!, my progesterone levels were really good, so I feel ok w plan! Randomized trials are needed to determine whether high-dose letrozole might actually be optimal as a result of that I to... Upon estradiol suppression may not be the only comment my doctors have made is I. ; 108 ( 4 ):568-571. doi: 10.1016/j.fertnstert.2006.03.044 I responded super quickly to my normal of... Leads to poor egg quality and it 's over 3000 for one as! If its or quite there ), but usually only one ovary a! Other advanced features are temporarily unavailable Arslan M, Oehninger S. Fertil Steril the past clomid ovulated! Weeks to find out and do not occur for as long as 2 months [ 14 ] doing letrozole. Two follicular diameters perpendicular to each other cycle management get any kind of LH detected! W that plan iui was performed next day but we did n't conceive we!

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